2013 Fiscal Year Final Research Report
Determination of N-nitrosamines at sub-ppt levels in tap water
| Project/Area Number |
23760506
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Civil and environmental engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | N-ニトロソジメチルアミン / 消毒副生成物 / 水道水 / 化学発光 / ルミノール / HPLC / 光化学反応 |
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| Research Abstract |
In recent years, N-nitrosodimethylamine (NDMA) which are potent mutagenic and carcinogenic compound in humans has been obtained as the byproducts of chlorine disinfection in drinking water supplies. Therefore, a sensitive and simple method for monitoring NDMA in tap water is urgently required. Recently, I developed a novel ultra-sensitive determination method for nitrosamines. This method is based on online UV irradiation after high-performance liquid chromatographic separation and subsequent luminol chemiluminescence detection.
In this study, I proposed a simple preparation procedure for measurement of NDMA in tap water. Furthermore, the developed method was used to monitor NDMA concentration in tap water. As the result, the seasonal change of concentration of NDMA in tap water was confirmed.
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