2013 Fiscal Year Final Research Report
Electrochemical device for evaluation of three-dimensional tissue organs
| Project/Area Number |
23760745
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Tohoku University |
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Principal Investigator |
INO Kosuke 東北大学, 環境科学研究科, 助教 (00509739)
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| Project Period (FY) |
2011 – 2013
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| Keywords | バイオセンサー / 電気化学分析 / バイオMEMS / 微小電極アレイ / 細胞解析 / マイクロ・ナノシステム |
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| Research Abstract |
In this study, we developed a novel electrochemical system and device for cell analysis. The system is based on redox cycling, which is used for signal amplification and addressable detection. By using the electrochemical system, many electrochemical sensors were successfully incorporated into a small chip device. Microwells were also placed onto each sensor for trapping cells. We developed several kinds of devices containing interdigitated array electrodes, ring-ring electrodes, ring-disk electrodes, and applied the devices for bioassays. By using the devices, cell activity and enzyme activity were successfully evaluated, indicating that the system and device are useful for cell analysis.
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[Remarks] 平成26年度電気化学会論文賞、2014年3月30日、電気化学会、伊野浩介、西條 拓、菅野佑介、小沢文智、新井俊陽、高橋 康史 、珠玖 仁 、末永 智一 、Electrochemical Device with Interdigitated Ring Array Electrodes for Investigating the Relationship between Cardiomyocyte Differentiation from Embryonic Stem Cells and Alkaline Phosphatase Activity
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[Remarks] 平成25年度トーキン科学技術賞、2014年3月4日、トーキン科学技術振興財団、伊野浩介、バイオイメージングに向けた電気化学チップデバイスの開発
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[Remarks] 平成24年度化学とマイクロ・ナノシステム研究会若手優秀賞、2013年5月23日、化学とマイクロ・ナノシステム学会、伊野浩介、レドックスサイクルによる高感度・網羅的電気化学チップデバイスの開発
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[Remarks] 第18回青葉工学研究奨励賞、2012年12月7日、青葉工学振興会、伊野浩介、網羅的電気化学測定に向けた新規測定システムの開発
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[Remarks] Best Presentation Award SSAS 2012、Sendai Sympojium on Analytical Sciences 2012 Organizing Committee、Kosuke Ino, Hitoshi Shiku, Tomokazu Matsue、Electrochemical imaging device consisting of 256 local redox cycling-based electrochemical sensors for high-throughput cell analysis
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[Remarks] RSC Best Poster Presentation Award、RSC Publishing、Kosuke Ino、Local redox cycling-based electrochemical chip devices containing 256 electrochemical sensors for cell analysis、RSC-JAIMA Symposium on Human Health and Dioagnostics JASIS 2012, Tokyo, Japan
