2012 Fiscal Year Final Research Report
Analysis on tolerance of polyploid plants to DNA damage
| Project/Area Number |
23770007
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | National Institute of Genetics |
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Principal Investigator |
INAGAKI Soichi 国立遺伝学研究所, 総合遺伝研究系, 助教 (00597883)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 植物 / 倍数性 / ゲノム維持 / 遺伝 |
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| Research Abstract |
We explored the molecular mechanisms of tolerance of polyploid plants to DNA damage using genetic analysis. We found that some genes that are involved in the homologous recombination are required for the tolerance. This result suggests that polyploid plants have a different mechanism of the DNA repair than diploid plants. In addition, we found that the polyploid of mutants for DNA repair genes frequently showed developmental abnormality, suggesting that the proper development of polyploid plants needs DNA repair pathway
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[Journal Article] Programmed induction of endoreduplication by DNA double-strand breaks in Arabidopsis2011
Author(s)
Sumiko Adachi, Kazunari Minamisawa, Yoko Okushim, Soichi Inagaki, Kaoru Yoshiyama, Youichi Kondou, Eli Kaminuma, Mika Kawashima, Tetsuro Toyod, Minami Matsui, Daisuke Kurihara, Sachihiro Matsunaga, Masaaki Umeda
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Journal Title
Proc. Natl. Acad. Sci. U.S.A
Volume: 108
Pages: 10004-10009
DOI
Peer Reviewed
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