2012 Fiscal Year Final Research Report
Molecular mechanism of a phenotypic adaptation to establishment of a synthetic bacterial mutualism
| Project/Area Number |
23770021
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Ecology/Environment
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
HOSODA Kazufumi 大阪大学, 大学院・情報科学研究科, 招へい准教授 (30515565)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 個体群 / 実験室内共生系 |
|---|
| Research Abstract |
Mutualism is ubiquitous in nature, and its establishment and evolution are important issues in ecology. To understand how organisms adapt to the first encounter with another organism to establish and evolve mutualism, experimental reconstruction of these processes is a useful strategy. Previously, we experimentally simulated the establishment of mutualism using two genetically-engineered auxotrophic strains of Escherichia coli, and found that one strain rapidly changed its phenotype, eventually leading to the establishment of the mutualism. Here we show not only the molecular basis of the observed phenotypic change, but also the experimental evolution of this mutualism.
|
