Chemical genetics analysis of secondary cell wall formation in protoxylem

2014 Fiscal Year Final Research Report

• Project/Area Number: 23770054
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: Nara Institute of Science and Technology
• Principal Investigator: YONEDA Arata 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (50553715)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: ケミカルバイオロジー / 道管 / 原生木部道管 / 二次細胞壁 / サルフォンアミド / サルファメチゾール / 表層微小管

Outline of Final Research Achievements

To clarify the mechanisms of secondary cell wall (SCW) formation during xylem vessel differentiation, we have screened the chemicals which affect the SCW formation. As a result, we could identify a compound sulfamethizole (SMZ), which had a novel bioactivity to induce abnormal branching and bending in spiral protoxylem SCWs. SMZ induced aberrant branching and bending cortical microtubules specifically during vessel cell differentiation, meaning that SMZ is a novel inhibitor against SCW formation mechanism in protoxylem and that SMZ could be an novel tool to investigate it further.

Free Research Field

植物細胞壁