2012 Fiscal Year Final Research Report
Structure-activity relationship of paralytic factors of green lacewings
| Project/Area Number |
23780118
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Ehime University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 生物活性物質 / ニッポンクサカゲロウ / 麻痺活性物質 / 農薬科学 |
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| Research Abstract |
A fraction containing a paralytic substance purified from Chrysoperla nipponensisusing the various column chromatographies was found to show the acute toxicity against houseflies. A target band of the SDS PAGE gel was digested by proteases to elucidate parts of its amino acid sequence using the LC-MS/MS. Some PCR products were then amplified using the degenerated primers, which were designed based on the elucidated amino acid sequences.
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Research Products
(4 results)
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[Journal Article] Synthesis of imidacloprid derivatives with a chiral alkylated imidazolidine ring and evaluation of their insecticidal activity and affinity to the nicotinic acetylcholine receptor.2012
Author(s)
Nishiwaki, H., Kuriyama, M., Nagaoka, H., Kato, A., Yamauchi, S., Shuto, Y.
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Journal Title
Bioorg. Med. Chem.
Volume: 20 (21)
Pages: 6305-6312
Peer Reviewed
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