2012 Fiscal Year Final Research Report
Identification of TNF pathway modulator and implications for immune response in kuruma shrimp
| Project/Area Number |
23780207
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General fisheries
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| Research Institution | Fisheries Research Agency |
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Principal Investigator |
MEKATA Tohru 独立行政法人水産総合研究センター, 増養殖研究所病害防除部, 研究員 (40597944)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 水族生体防御 |
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| Research Abstract |
To gain an insight of the function of shrimp TNF at protein level, proteome analysis has been done in kuruma shrimp (Marsupenaeus japonicus) with recombinant TNF administration, gene silencing by dsRNA, and pathogen stimulation. Putative s-adenosylhomocysteine hydrolase were up-regulated after recombinant TNF injection and down-regulated after gene knockdown and exposure to pathogens.
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[Journal Article] The SOCS and STAT from JAK/STAT signaling pathway of kuruma shrimp Marsupenaeus japonicus: molecular cloning, characterization and expression analysis.2013
Author(s)
Okugawa S, Mekata T, Inada M, Kihara K, Shiki A, Kannabiran K, Kono T, Sakai M, Yoshida T, Itami T, Sudhakaran R.
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Journal Title
Molecular & Cellular Probes
Volume: 27(1)
Pages: 6-14
DOI
Peer Reviewed
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