2013 Fiscal Year Final Research Report
Functional features of esophageal neural control and muscle cells in neonatal animals
| Project/Area Number |
23780291
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Basic veterinary science/Basic zootechnical science
|
|---|
| Research Institution | Gifu University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | 食道 / 新生子 / 腸神経系 / 筋細胞 / 食道疾患 |
|---|
| Research Abstract |
The aim of this study was to clarify postnatal changes in neural control of esophageal motility and characters of esophageal muscles in rats. The main findings are: (1) the vagus nerves directly innervate both the striated and smooth muscles and control their motility in the early neonatal period, (2) striated muscle reactions gradually enlarge with age in days, whereas smooth muscle responses decline during the first week after birth, (3) sensitivity of acetylcholine to the esophageal striated muscle decrease with age in days, (4) the gamma-subunit of nicotinic acetylcholine receptors and gap junction are expressed in the neonatal esophagus but not the adult esophagus. These specific features might contribute to appropriate regulation of esophageal motility in neonatal animals.
|
-
-
[Journal Article] Development of longitudinal smooth muscle in the posterior mesenteric artery and purinergic regulation of its contractile responses in chickens2013
Author(s)
Shiina, T., Koga, M., Saito, S., Atoji, Y., Takewaki, T., Shimizu, Y.
-
Journal Title
J Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol.
Volume: 199
Pages: 857-865
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
