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2013 Fiscal Year Final Research Report

Neural mechanism mediating the mating-induced ovulation in the musk shrew, a reflex ovulator

Research Project

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Project/Area Number 23780292
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Basic veterinary science/Basic zootechnical science
Research InstitutionNagoya University

Principal Investigator

INOUE Naoko  名古屋大学, 生命農学研究科, 助教 (90377789)

Project Period (FY) 2011 – 2012
Keywordsスンクス / 交尾排卵 / 交尾刺激 / キスペプチン / 性腺刺激ホルモン放出ホルモン
Research Abstract

The present study suggests that the mating stimulus activates kisspeptin neurons in the preoptic area (POA), and then stimulates gonadotropin-releasing hormone (GnRH) release to induce ovulation in the musk shrew, a reflex ovulator. The gracile nucleus, the sensory spinal nerve terminal, and the solitary nucleus, the sensory vagus nerve terminal, may mediate the mating stimulus to the POA kisspeptin neurons in the musk shrew.

  • Research Products

    (14 results)

All 2014 2013 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (10 results)

  • [Journal Article] Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain2012

    • Author(s)
      Tomikawa J, Uenoyama Y, Ozawa M, Fukanuma T, Takase K, Goto T, Abe H, Ieda N, Minabe S, Deura C, Inoue N, Sanbo M, Tomita K, Hirabayashi M, Tanaka S, Imamura T, Okamura H, Maeda K, Tsukamura H
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 109 Pages: E1294-1301

    • Peer Reviewed
  • [Journal Article] キスペプチンと生殖腺刺激ホルモン放出ホルモン(GnRH)分泌2012

    • Author(s)
      井上直子,束村博子,前多敬一郎
    • Journal Title

      Clinical Neuroscience

      Volume: 30巻 Pages: 220-222

  • [Journal Article] 卵胞発育の中枢制御機構2011

    • Author(s)
      井上直子,上野山賀久,大蔵聡,束村博子,前多敬一郎
    • Journal Title

      Hormone Frontier in Gynecology

      Volume: 18巻 Pages: 391-394

  • [Journal Article] Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus)2011

    • Author(s)
      Inoue N, Sasagawa K, Ikai K, Sasaki Y, Tomikawa J, Oishi S, Fujii N, Uenoyama Y, Ohmori Y, Yamamoto N, Hondo E, Maeda K, Tsukamura H
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 108 Pages: 17527-17532

    • Peer Reviewed
  • [Presentation] スンクスにおける交尾排卵制御機構2014

    • Author(s)
      井上直子
    • Organizer
      第8回スンクス研究会
    • Place of Presentation
      自治医科大学
    • Year and Date
      2014-03-26
  • [Presentation] 遺伝子改変スンクス作製に向けた胚移植法の確立2013

    • Author(s)
      堀田章徳、山本彩子、後藤哲平、平林真澄、前多敬一郎、大森保成、本道栄一、井上直子
    • Organizer
      日本繁殖生物学会第106回大会
    • Place of Presentation
      東京農工大学
    • Year and Date
      20130912-14
  • [Presentation] 交尾刺激を伝達する神経回路の解明2013

    • Author(s)
      大久保紫織、大森保成、山本直之、本道栄一、井上直子
    • Organizer
      日本繁殖生物学会第106回大会
    • Place of Presentation
      東京農工大学
    • Year and Date
      20130912-14
  • [Presentation] スンクスにおける生殖制御機構2013

    • Author(s)
      井上直子
    • Organizer
      スンクスを用いた脳-末梢連関研究
    • Place of Presentation
      埼玉大学
    • Year and Date
      2013-02-16
  • [Presentation] Analysis of promoter region of gonadotropin-releasing hormone 2 gene in the musk shrew (Suncus murinus)2012

    • Author(s)
      Hotta A, Hondo E, Ohmori Y, Inoue N
    • Organizer
      The 4th Congress of Asian Association of Veterinary Anatomists
    • Place of Presentation
      Thailand, Phuket
    • Year and Date
      20121024-26
  • [Presentation] Elucidation of neuronal circuits that transmit the mating stimulus in the musk shrew (Suncus murinus)2012

    • Author(s)
      Ohkubo S, Hondo E, Ohmori Y, Inoue N
    • Organizer
      The 4th Congress of Asian Association of Veterinary Anatomists
    • Place of Presentation
      Thailand, Phuket
    • Year and Date
      20121024-26
  • [Presentation] スンクスにおけるGnRH2ニューロンの免疫組織化学的解析2011

    • Author(s)
      猪飼耕太郎、長谷川喜久、山本直之、大森保成、本道栄一、井上直子
    • Organizer
      日本繁殖生物学会第104回大会
    • Place of Presentation
      盛岡
    • Year and Date
      20110915-17
  • [Presentation] スンクスの交尾排卵制御機構におけるキスペプチンニューロンの関与2011

    • Author(s)
      笹川佳倫、猪飼耕太郎、上野山賀久、本道栄一、前多敬一郎、束村博子、井上直子
    • Organizer
      日本繁殖生物学会第104回大会
    • Place of Presentation
      盛岡
    • Year and Date
      20110915-17
  • [Presentation] Involvement of kisspeptin neurons in reflex ovulation in the musk shrew (Suncus murinus)2011

    • Author(s)
      Inoue N, Sasagawa K, Uenoyama Y, Hondo E, Maeda K, Tsukamura H
    • Organizer
      The 2nd World Congress on Reproductive Biology (WCRB)
    • Place of Presentation
      Australia, Cairns
    • Year and Date
      2011-10-11
  • [Presentation] 井上直子、スンクスの脳におけるGnRH2ニューロンの局在2011

    • Author(s)
      猪飼耕太郎、大森保成、本道栄一
    • Organizer
      東海実験動物研究会
    • Place of Presentation
      名古屋市立大学
    • Year and Date
      2011-07-23

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Published: 2015-06-25  

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