2014 Fiscal Year Final Research Report
Study for development of a novel therapy for canine atopic dermatitis focused on signaling proteins
| Project/Area Number |
23780321
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical veterinary science
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| Research Institution | Gifu University |
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Principal Investigator |
SHIBATA Sanae 岐阜大学, 応用生物科学部, 准教授 (20588917)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Keywords | canine / keratinocytes / HB-EGF |
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| Outline of Final Research Achievements |
We focused on EGF family in order to develop a novel therapy for canine atopic dermatitis. In this study, we studied about HB-EGF which mainly expresses in epidermis. We succeeded partial cloning of canine HB-EGF mRNA. In addition, the HB-EGF expression in canine keratinocytes cell line didn't change after stimulation with inflammatory cytokine.
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| Free Research Field |
臨床獣医学
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