2013 Fiscal Year Final Research Report
Application of exercise therapy in diabetic dogs
| Project/Area Number |
23780328
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical veterinary science
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| Research Institution | Nippon Veterinary and Life Science University |
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Principal Investigator |
MORI AKIHIRO 日本獣医生命科学大学, 獣医学部, 助教 (60549559)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 運動療法 / 犬 / 糖尿病 |
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| Research Abstract |
In this study, we investigated whether therapeutic exercise affects blood biochemical parameters and muscular mRNA expression in diabetic dogs. No significant difference was observed between the fasting blood glucose concentrations before and after exercise. However, the level of glycated albumin was significantly decreased after exercise. No significant difference was observed between before and after exercise in the muscular mRNA expression of insulin signaling and glucose metabolism genes including insulin receptor substrate -1 and -2. In summary, therapeutic exercise decreased glycated albumin levels and thus ameliorated glycemic control in diabetic dogs.
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Research Products
(3 results)
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[Journal Article] Characterization and comparison of insulin resistance induced by Cushing Syndrome or diestrus against healthy control dogs as determined by euglycemic- hyperinsulinemic glucose clamp profile glucose infusion rate using an artificial pancreas apparatus2012
Author(s)
Fukuta H, Mori A, Urumuhan N, Lee P, Oda H, Saeki K, Kurishima M, Nozawa S, Mizutani H, Mishina S, Arai T, Sako T
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Journal Title
J Vet Med Sci
Volume: Vol 74
Pages: 1527-1530
Peer Reviewed
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