2012 Fiscal Year Final Research Report
The development of nucleophilic addition to α-position of ketones by using N-alkoxyenamines and its application to asymmetric reactions
| Project/Area Number |
23790032
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kobe Pharmaceutical University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 有機化学 / 極性転換 / 窒素-酸素結合 / エナミン |
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| Research Abstract |
The compounds bearing hetero atom-hetero atom bonds such as N-O bond has very interesting reactivity. We have developed the a-heteroarylation of ketones and a-arylation allylation reaction of aldehyde by using the Umpolung reaction of N-alkoxyenamines. Furthermore, the sequential retro-ene addition readction of N-alkokyenamides has been developed.
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Research Products
(12 results)
