2012 Fiscal Year Final Research Report
Microcapsule preparation by in situ polymerization on surface of micro particles
| Project/Area Number |
23790040
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
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| Research Institution | Tohoku University |
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Principal Investigator |
SATO Katsuhiko 東北大学, 大学院・薬学研究科, 助教 (80400266)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 機能性カプセル / 刺激応答カプセル / 機能性薄膜 / 表面重合 / ドラックデリバリーシステム |
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| Research Abstract |
Poly(methyl methacrylate) microcapsules were prepared by the in situ polymerization of methyl methacrylate and N,N'-methylenebisacrylamide on the surface of CaCO_3 particles, followed by the dissolution of the CaCO_3 core in ethylenediaminetetraacetic acid solution. The microcapsules were characterized using fluorescence microscopy, atomic force microscopy, scanning electron microscopy, and Fourier transform infrared spectroscopy. Similarly, the microcapsules were prepared by RAFT reagent of particles surface.
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