2012 Fiscal Year Final Research Report
Synthesis and anti-viral evaluation of 4'-substituted nucleoside derivatives
| Project/Area Number |
23790141
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Drug development chemistry
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 生物活性物質 |
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| Research Abstract |
With an aim to discovery of novel anti-viral/tumor agents, I have developed a new method for the synthesis of 4’-substituted cordycepin derivatives by substitution of a phenylsulfanyl leaving group. Anti-viral evaluation of 4’-substituted cordycepin found some compounds having an activity against RNA virus.
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