2012 Fiscal Year Final Research Report
EMT-targeted molecular therapy for renal cell carcinoma
Project/Area Number |
23790417
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Human pathology
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Research Institution | Keio University |
Principal Investigator |
MIKAMI Shuji 慶應義塾大学, 医学部, 助教 (20338180)
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Project Period (FY) |
2011 – 2012
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Keywords | 上皮-間葉転換 / 腎細胞癌 / TNF-α / 転移 / 分子標的薬 |
Research Abstract |
TNF-α and CD44 were expressed in carcinoma cells of high-grade clear cell renal cell carcinomas (ccRCCs) and the expression levels showed positive correlation with primary tumor stage and distant metastasis. Elevated expression of TNF-α and CD44 was pr
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Research Products
(13 results)
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[Journal Article] The prognostic significance of vasohibin-1 expression in patients with upper urinary tract urothelial carcinoma2012
Author(s)
Miyazaki Y, Kosaka T, Mikami S, Kikuchi E, Tanaka N, Maeda T, Ishida M, Miyajima A, Nakagawa K, Okada Y, Sato Y, Oya M
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Journal Title
Clin Cancer Res
Volume: 18
Pages: 4145-53
Peer Reviewed
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[Journal Article] Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis2012
Author(s)
Endo M, Nakano M, Kadomatsu T, Fukuhara S, Kuroda H, Mikami S, Hato T, Aoi J, Horiguchi H, Miyata K, Odagiri H, Masuda T, Harada M, Horio H, Hishima T, Nomori H, Ito T, Yamamoto Y, Minami T, Okada S, Takahashi T, Mochizuki N, Iwase H, Oike Y
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Journal Title
Cancer Res
Volume: 72(7)
Pages: 1784-94
Peer Reviewed
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