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2012 Fiscal Year Final Research Report

Migratory potential of chondrocytes in human osteoarthritic cartilage

Research Project

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Project/Area Number 23790420
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Human pathology
Research InstitutionKeio University

Principal Investigator

KIMURA Tokuhiro  慶應義塾大学, 医学部, 助教 (40445200)

Project Period (FY) 2011 – 2012
Keywords関節 / 軟骨 / 変形性関節症 / 細胞運動 / 細胞生物学
Research Abstract

Migratory potential of osteoarthritic (OA) chondrocytes was examined by monolayer wound assay using cultured chondrocytes isolated from human OA cartilage samples. Migration of OA chondrocytes was regulated by cytokines/growth factors that are involved

  • Research Products

    (5 results)

All 2012 2011 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) Remarks (1 results)

  • [Journal Article] Semaphorin 3A is expressed in human osteoarthritic cartilage and antagonizes vascular endothelial growth factor 165-promoted chondrocyte migration: An implication for chondrocyte cloning2011

    • Author(s)
      Okubo M, Kimura T, Fujita Y, Mochizuki S, Niki Y, Enomoto H, Suda Y, Toyama Y, Okada Y.
    • Journal Title

      Arthritis Rheum

      Volume: 63 Pages: 3000-3009

    • Peer Reviewed
  • [Presentation] クローニング病変から見た関節軟骨変性の病態(シンポジウム 軟骨エイジング-そのメカニズムと評価)2012

    • Author(s)
      木村徳宏
    • Organizer
      第40回日本関節病学会
    • Place of Presentation
      鹿児島市民文化ホール(鹿児島県).(招待講演)
    • Year and Date
      2012-11-09
  • [Presentation] ヒト変形性関節症軟骨においてRECKは高発現し軟骨細胞のクローニングに関わる2012

    • Author(s)
      木村徳宏, 岡田愛子, 谷田部拓, 大久保匡, 戸山芳昭, 野田亮, 岡田保典
    • Organizer
      第25回日本軟骨代謝学会
    • Place of Presentation
      ウィルあいち(愛知県)(招待講演)
    • Year and Date
      2012-03-10
  • [Presentation] 関節軟骨のリモデリング(シンポジウム 慢性炎症下における組織リモデリング)2011

    • Author(s)
      木村徳宏, 岡田保典
    • Organizer
      第57回日本病理学会秋期特別総会
    • Place of Presentation
      日本教育会館(東京都)(招待講演)
    • Year and Date
      2011-11-17
  • [Remarks]

    • URL

      http://keio-okada-lab.jp/

URL: 

Published: 2014-09-25  

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