2012 Fiscal Year Final Research Report
The development of novel colorectal cancer screening method using exosomal antisense RNA in serum
| Project/Area Number |
23790613
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Laboratory medicine
|
|---|
| Research Institution | Hirosaki University |
|---|
Principal Investigator |
CHIBA Mitsuru 弘前大学, 大学院・保健学研究科, 助教 (20583735)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 腫瘍検査学 / アンチセンス RNA |
|---|
| Research Abstract |
Exosomes are microvesicles that are released from various cells into the extracellular space. It has been reported that the components within exosomes vary according to the type of secreted cell. In the present study, we identified a species of mRNAs, microRNAs, and natural antisense RNAs within the exosomes secreted from the three colorectal cancer (CRC) cell lines. We discovered that their natural antisense RNAs were within exosomes for the first time in the present study. Currently, the searching of exosomal CRC-specific natural antisense RNAs in serum has been performed.
|
Research Products
(2 results)
