2012 Fiscal Year Final Research Report
Plasma Endothelin-1 Level Is a Predictor of 10-Year Mortality in a General Population
| Project/Area Number |
23790714
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Public health/Health science
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| Research Institution | Kurume University |
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Principal Investigator |
YOKOI Kanako 久留米大学, 医学部, 助教 (80569385)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 疫学 / エンドセリン / 死亡率 / 追跡理 |
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| Research Abstract |
Plasma ET-1 level is a predictor of mortality in patients with several types of cancers. However, all previous mortality data have been derived from patients with existing pathological cardiovascular disease and malignancies. Accordingly, we examined whether the plasma ET-1 level would predict 10-year cardiovascular, cancer and all-cause deaths in a general population. This is the first report demonstrating that the plasma ET-1 level is a predictor of 10-year mortality in subjects without apparent cardiovascular disease or malignancies in the general population.
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[Journal Article] New computer model for prediction of individual 10-yearmortality on the basis of conventional atherosclerotic risk factors.2013
Author(s)
Ogata K, MiyamotoT, Adachi H, Hirai Y, Enomoto M, Fukami A, Yokoi K, Kasahara A, Tsukagawa E, Yoshimura A, Obuchi A, Nakamura S, Imaizumi T.
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Journal Title
Atherosclerosis.
Volume: 227
Pages: 159-164
DOI
Peer Reviewed
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[Journal Article] High serum N-acetyl- β -d-glucosaminidase activity is predictor of 28-year mortality in a population of community-dwelling Japanease ? the Tanushimaru study.2013
Author(s)
Yoshikawa K, Adachi H, Hirai Y, Enomoto M, Fukami A, Ogata K, Tsukagawa E, Kasahara A, Yokoi K, Okina N, Obuchi A, Yoshimura A, Nakamura S, Imaizumi T.
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Journal Title
J Am Geriatr Soc.
Volume: 61(3)
Pages: 467-468
DOI
Peer Reviewed
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[Journal Article] High level of plasma remnant-like particle cholesterol may predispose to development of hypertention in normotensive subjects.2013
Author(s)
Kasahara A, Adachi H, Hirai Y, Enomoto M, Fukami A, Yoshikawa K, Esaki E, Yokoi K, Ogata K, Tsukagawa E, Obuchi A, Yoshimura A, Nakamura S, Imaizumi T.
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Journal Title
Am J Hypertens.
Volume: 26(6)
Pages: 793-798
DOI
Peer Reviewed
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[Journal Article] Serum hepatocyte growth factor and cancer mortality in an apparently healthy Japanese population.2012
Author(s)
Otsuka M, Adachi H, Jacobs DR Jr, Hirai Y, Enomoto M, Fukami A, Kumagae S, Nanjo Y, Yoshikawa K, Esaki E, Kumagai E, Yokoi K, Ogata K, Tsukagawa E, Kasahara A, Ohbu K, Imaizumi T.
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Journal Title
J Epidemiol.
Volume: 22(5)
Pages: 395-401
Peer Reviewed
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[Journal Article] Plasma aldosterone levels and development of insulin resistance: prospective study in a general population.2011
Author(s)
Kumagai E, Adachi H, Jacobs DR Jr, Hirai Y, Enomoto M, Fukami A, Otsuka M, Kumagae S, Nanjo Y, Yoshikawa K, Esaki E, Yokoi K, Ogata K, Kasahara A, Tsukagawa E, Ohbu-Murayama K, Imaizumi T.
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Journal Title
Hypertension.
Volume: 58(6)
Pages: 1043-1048
DOI
Peer Reviewed
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[Journal Article] LDL-C/HDL-C ratio predicts carotid intima-media thickness progression better than HDL-C or LDL-C alone.2011
Author(s)
Enomoto M, Adachi H, Hirai Y, Fukami A, Satoh A, Otsuka M, Kumagae S, Nanjo Y, Yoshikawa K, Esaki E, Kumagai E, Ogata K, Kasahara A, Tsukagawa E, Yokoi K, Ohbu-Murayama K, Imaizumi T.
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Journal Title
J Lipids.
Volume: 2011
Pages: 549137
DOI
Peer Reviewed
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