2012 Fiscal Year Final Research Report
Central sleep apnea and sudden unexpected death in epilepsy (SUDEP)in patients with intractable epilepsy
| Project/Area Number |
23790971
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurology
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| Research Institution | Tohoku University |
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Principal Investigator |
JIN Kazutaka 東北大学, 大学院・医学系研究科, 講師 (20436091)
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| Project Period (FY) |
2011 – 2012
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| Keywords | てんかん学 / 臨床神経生理学 / 臨床神経学 / 睡眠時無呼吸 / 自律神経 |
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| Research Abstract |
No epilepsy patients revealed significant central sleep apneas. A patient with bilateral temporal lobe epilepsy showed that central apneas precede ictal EEG onset in seizures arising from left temporal region and follow it in those arising from right. In addition, seizures arising from left and right temporal regions had different patterns of heart rate changes from each other. Ictal central apnea and heart rate changes would be closely associated with seizure lateralization.
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