2013 Fiscal Year Final Research Report
crosstalk of C-type natriuretic peptide in the endochondral ossification
| Project/Area Number |
23791056
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Kyoto University |
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Principal Investigator |
FUJII Toshihito 京都大学, 医学(系)研究科(研究院), 助教 (50537347)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 軟骨 / ナトリウム利尿ペプチド / 骨 |
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| Research Abstract |
In this study, I showed that C-type natriuretic peptide(CNP) attenuated downstream signals of BMP in the endochondral ossification. Now, therefore, CNP may be the target of drug discovery for Fibrodysplasia Ossificans Progressiva(FOP), that is a refractory disease of muscle and bone caused by runaway of BMP signals.
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