2012 Fiscal Year Final Research Report
Roles of bone morphogenetic protein-6 inaldosterone regulation by adrenocortical cells
| Project/Area Number |
23791058
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 内科学 / 内分泌 / 副腎 / ステロイド / 成長因子 |
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| Research Abstract |
In the present study, we examined the in vivo roleof BMP-6 in regulation of aldosterone by neutralizing endogenous BMP-6 in rats treated with immunization against BMP-6. It was suggested that endogenous BMP-6 is functionally linked to aldosterone synthesis in the adrenal cortex in vivo.
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