2012 Fiscal Year Final Research Report
Construction of the methodology to enable the rational dosage setting of various antibiotics based on the available TDM data.
| Project/Area Number |
23791133
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Infectious disease medicine
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 感染症治療学 / 個別化投与量設計 |
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| Research Abstract |
In this project, it is suggested that the clearances of urinary excreted antibiotics are correlated each other. In addition, we proposed the methodology which enables the exact estimation of clearances of antibiotics in patients with acute kidney injury or patients receiving blood purification therapy. Based on these results, the methodology which provides the theoretical dosage settings of various antibiotics using serum concentration data of some kinds of antibiotics, will be established.
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