2012 Fiscal Year Final Research Report
A study regarding aberrant methylation of Retrotransposon-like 1 gene in human placentas of intrauterine growth restriction
| Project/Area Number |
23791225
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 子宮内胎児発育遅延 / 胎盤 / レトロトランスポゾン由来遺伝子(Retrotransposon-like 1: Rtl1) / 遺伝子多型 / 血管内皮増殖因子(VEGF) / レニン・アンジオテンシン系(RAS) |
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| Research Abstract |
A purpose of this study was to clarify the aberrant methylation of Retrotransposon-like 1 gene (Rtl1) in human placenta of intrauterine growth retardation (IUGR). We could not find different methylation pattern of Rtl1in human placentas of IUGR and healthy newborns. However, we detected the VEGFand RASpolymorphisms that are associated with IUGR.
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