2012 Fiscal Year Final Research Report
Development of novel therapies for atopic dermatitis
| Project/Area Number |
23791244
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Hokkaido University |
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Principal Investigator |
HAMASAKA Asuka 北海道大学, 大学院・医学研究科, 非常勤講師 (60598382)
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| Project Period (FY) |
2011 – 2012
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| Keywords | アトピー性皮膚炎 / モデルマウス / 新規治療法 |
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| Research Abstract |
Flaky tail mice carry a 1bp deletion in a gene encoding filaggrin and develop spontaneous dermatitis. In this study, we used flaky tail mice as a model of atopic dermatitis. Improvement of dermatitis was observed after treatment with MIF-DNA vaccine or DHEMQ. These data suggest that both MIF-DNA vaccine and DHMEQ be a novel therapeutic option for atopic dermatitis.
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Research Products
(1 results)
