2012 Fiscal Year Final Research Report
The role of the TWIST in Squamous cell carcinoma
| Project/Area Number |
23791259
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 皮膚腫瘍学 |
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| Research Abstract |
We examined the relationship between cutaneous Squamous cell carcinoma(cSCC) and TWIST, Snail, E-cadherin and Human papilloma virus(HPV). TWIST, Snail were over expressed in invasive cSCCs. On the other hand E-cadherin expressed low level in invasive cSCCs. We could not find the relationship between cSCCs and HPV. In cSCC insitu, these expression levels were same with invasive cases. Cell membrenes of keratinocytes were also stained with E-cadherin.
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