2012 Fiscal Year Final Research Report
Symptomatology of focal brain injury and diffuse axonal injury, by applying diffuse tensor imaging
| Project/Area Number |
23791328
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Kyoto University |
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Principal Investigator |
UEDA Keita 京都大学, 医学研究科, 助教 (60573079)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 外傷性脳損傷 / 情動認知 / 社会行動障害 |
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| Research Abstract |
In the two types of traumatic brain injury, focal brain injuries, especially in the orbitofrontal cortex, was found to lead to the dysfunction of the cognition of the facial expression of others, which resulted in the deficit in social cognition. In the diffuse axonal injuries, it became clear that volume reduction tended to be found in some particular brain regions, including not only central structures such as anterior cingulate cortex and thalamus but also insular cortex in the gray matter, and splenium of corpus callosum in the white matter. As to the characteristics in cognitive dysfunction, those with diffuse axonal injury showed significantly lower ability in processing speed found in the trail making test and in the Wechsler Adult Intelligence Scale. Concerning to the psychiatric symptoms like apathy, there was no significant differences between the two groups.
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[Journal Article] Abnormal asymmetry of white matter integrity in schizophrenia revealed by voxelwise diffusion tensor imaging.2011
Author(s)
Miyata J, Sasamoto A, Koelkebeck K, Hirao K, Ueda K, Kawada R, Fujimoto S, Tanaka Y, Kubota M, Fukuyama H, Sawamoto N, Takahashi H, Murai T.
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Journal Title
DOI
Peer Reviewed
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[Journal Article] Subthalamic nucleus deep brain stimulation restores normal rapid eye movement sleep in Parkinson's disease.2011
Author(s)
Nishida N, Murakami T, Kadoh K, Tohge R, Yamanegi M, Saiki H, Ueda K, Matsumoto S, Ishikawa M, Takahashi JA, Toda H.
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Journal Title
Mov Disord.
Volume: 26(13)
Pages: 2418-22
DOI
Peer Reviewed
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