2013 Fiscal Year Final Research Report
Evaluation of segmental liver reserve using functional imaging technique.
| Project/Area Number |
23791405
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Shinshu University |
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Principal Investigator |
YAMADA Akira 信州大学, 医学部附属病院, 助教 (80419407)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 肝予備能 / 肝細胞特異性造影剤 / MRI / コンパートメントモデル / HUI |
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| Research Abstract |
We established a compartment model analysis of hepatocellular specific contrast agent, gadoxetic disodium using magnetic resonance (MR) imaging that can evaluate hepatic hemodynamics and function independently. Further more, we established Hepatocellular Uptake Index, HUI that is a quantitative index of hepatic reserve by simplification of the compartment model. HUI can be well correlated with indocyanine green (ICG) clearance test; further more, a segmental hepatic reserve can be evaluated by remnant HUI that can be derived from HUI.
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