2012 Fiscal Year Final Research Report
Feasibility study of Fiber-Tracted Radiation Therapy for Malignant Glioma
| Project/Area Number |
23791428
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 放射線治療学 / 拡散テンソル解析 |
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| Research Abstract |
The relationship with the pattern of failure for glioblastoma and nerve fibers inside the brain has not been considered on the radiotherapy for glioblastoma. We published a paper regarding recurrence pattern of malignant glioma and effectiveness of MIB-1 Labeling index for predicting the pattern of failure in glioblastoma. In addition, we evaluated the efficacy of diffusion tensor imaging into radioation treatment planning. Our results suggested a possibility that Diffusion Tensor imaging can used to reduce the radiation dose to normal brain, and escalated the radiation dose to primary tumor.
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[Journal Article] Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index2012
Author(s)
K. Uehara, T. Sasayama, D. Miyawaki, H. Nishimura, K. Yoshida, Y. Okamoto, N. Mukumoto, H. Akasaka, M. Nishihara, O .Fujii, T. Soejima, K. Sugimura, E .Kohmura and R. Sasaki
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Journal Title
Radiation oncology
Volume: 7
Pages: 104-115
Peer Reviewed
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[Presentation] Combination Efficacy of MGMT Promoter Methylation Status and MIB-1 Labeling Index for Pattern of Recurrence in Glioblastoma Treated with Multimodal Treatment2012
Author(s)
K. Uehara, T. Sasayama, D. Miyawaki, M. Nishihara, K. Yoshida, H. Nishimura, Y. Okamoto, M. Nakayama, N. Mukumoto, H. Akasaka, K. Sugimura, R. Sasaki
Organizer
98th Scientific Assembly and Annual Meeting of The Radiological Society of North America
Place of Presentation
McComick Place Chicago
Year and Date
2012-11-30
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