2012 Fiscal Year Final Research Report
Functional analysis of Wnt-related genes concerning invasion andmetastasis of pancreas cancer
Project/Area Number |
23791552
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Digestive surgery
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Research Institution | University of Miyazaki |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Keywords | Dkk-1 遺伝子 / Wnt 遺伝子 |
Research Abstract |
WNT protein have a multiple functions concerning cancer in vasionand metastasis. We investigated DKK-1 protein concentration in the pancreatic juice,which shows inhibitory ability against WNT protein, for an early detection of the pancreascancer . Although no correlation can be identified between DKK-1 concentration andpancreas cancer , DKK-1 mRNA expression is elevated in the bile duct cancer as well aspancreas cancer
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