2012 Fiscal Year Final Research Report
Significant role of bone marrow derived cells in compensatory regenerative lung growth and wound healing.
| Project/Area Number |
23791571
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Thoracic surgery
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| Research Institution | 独立行政法人国立病院機構山ロ宇部医療センター (2012)
National Hospital Organization,Yamaguchi - Ube Medical Center (2011) |
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Principal Investigator |
TANAKA Toshiki 独立行政法人国立病院機構山ロ宇部医療センター, 臨床研究部, 医師 (50457305)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 呼吸器外科学 |
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| Research Abstract |
After left pneumonectomy, bone marrow-derived cells (BMCs) accumulated in the wound and contributed to tissue repair. This phenomenon was possibly addressed that BMCs was differentiated to myofibroblast and vascular endotjelial cells. BMCs which accumulated in the residual lung parenchyma after left pneumonectomy was possibly differentiated to alveolar cells and vascular endothelial cells, which would contribute to regeneration of lung tissue. BMCs would affect tissue repair during the lug regeneration.
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