2012 Fiscal Year Final Research Report
The identification of molecular targets for glioblastoma using mouse model transplanted transgenic neural stem cell
| Project/Area Number |
23791588
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kanazawa University |
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Principal Investigator |
TAMASE Akira 金沢大学, 医学系, 協力研究員 (10595458)
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| Project Period (FY) |
2011 – 2012
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| Keywords | グリオーマ / 幹細胞 / マウスモデル / 標的分子 / マイクロアレイ |
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| Research Abstract |
We explored the genes which overexpressed in glioma stem-like cells using the mouse glioma model transplanted transgenic neural stem cells. Glioma stem-like cells were labeled by Green Fluorescent Protein (GFP). The gene expression profiles of which cells are GFP positive or are GFP negative havebeen obtained by microarray data, respectively. Fifty candidate genes were picked up. Among them, two genes have been identified as promising genes.
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Research Products
(2 results)
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[Journal Article] Nucleostemin in injury-induced liver regeneration2012
Author(s)
Shugo H, Ooshio T, Naito M, Naka K, Hoshii T, Tadokoro Y, Muraguchi T, Tamase A, Uema N, Yamashita T, Nakamoto Y, Suda T, Kaneko S, Hirao A.
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Journal Title
Stem Cells Dev
Volume: 21(16)
Pages: 3044-54
DOI
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