2012 Fiscal Year Final Research Report
Neurorestorative therapy for Stroke based on PrPcprotein
Project/Area Number |
23791609
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Cerebral neurosurgery
|
Research Institution | Nagasaki University |
Principal Investigator |
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Project Period (FY) |
2011 – 2012
|
Keywords | stroke / PrPc / neuroprotection |
Research Abstract |
Our study clearly suggests that PrPc plays an important role against stroke. Although, the effect depends on the rodent strain, PrPc could provide neuro-protective or neuro-restrative effect and enhance functional recovery after stroke. In terms of the PrPc protein, total PrPc protein is preserved in stroke or vascular dementia and significantly reduced total PrPc protein in cerebrospinal fluid in Prion disease.
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Research Products
(7 results)