Simultaneous evaluation of the articular cartilage and subchondral bone with photoacoustic microscopy

2012 Fiscal Year Final Research Report

• Project/Area Number: 23791624
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Orthopaedic surgery
• Research Institution: Tohoku University
• Principal Investigator: HAGIWARA Yoshihiro 東北大学, 大学院・医学系研究科, 講師 (90436139)
• Project Period (FY): 2011 – 2012
• Keywords: 光音響顕微鏡装置 / 変形性関節症 / 超音波 / 非侵・接触型評価 / レーザー

Research Abstract

Photoacoustics (PA) imaging is the conversion of nano-second pulse lasers to ultrasound (US) by thermal expansion of the material. We evaluated the articular cartilage and subchondral bone with the PA method. It canIn the normal cartilage, low signal intensity was observed in the articular cartilage but high signal intensity in the cancellous bones in PA imaging. In the OA cartilage, higher signal intensity was observed in the articular cartilage and subchondral bone in PA imaging, which might indicate an increase of blood flow of them.

Research Products

• [Presentation] Three-dimensional Photoacoustic Imaging of Cartilage-Bone Complex (2013)
  • Author(s): Takuya Izumi, Mika Sato, Yutaka Yabe, YoshihiroHagiwara, Yoshifumi Saijo
  • Organizer: the International Congress on Ultrasonics(ICU 2013)
  • Place of Presentation: Singapore
  • Year and Date: 20130502-05
• [Presentation] PHOTOACOUSTIC IMAGING OF CARTILAGE-BONE COMPLEX (2013)
  • Author(s): Yoshihiro Hagiwara, Takuya Izumi, Yutaka Yabe, Kenji Kanazawa, Akira Ando, Yoshifumi Saijo, Eiji Itoi
  • Organizer: The 2013Osteoarthritis Research Society International World Congress, Philadelphia, Pennsylvania
  • Place of Presentation: USA
  • Year and Date: 20130418-21
• [Presentation] 半導体レーザーを用いたマウス膝軟骨の光音響イメージング (2012)
  • Author(s): 和泉拓哉,三井田佑輔,長岡亮,佐藤みか,松浦祐司,萩原嘉廣,西條芳文
  • Organizer: 第33回超音波エレクトロニクスの基礎と応用に関するシンポジウム
  • Place of Presentation: 千葉
  • Year and Date: 20121113-20121115
• [Presentation] Photoacoustic Imaging of Rat Knee Joint (2012)
  • Author(s): Takuya Izumi, Mika Sato, Yoshihiro Hagiwara, Yoshifumi Saijo
  • Organizer: 2012 IEEE International Ultrasonics Symposium
  • Place of Presentation: Dresden, Germany
  • Year and Date: 20121007-10
• [Presentation] 光音響顕微鏡によるマウス膝軟骨の観察 (2012)
  • Author(s): 和泉拓哉,三井田佑輔,長岡亮,佐藤みか,松浦祐司,萩原嘉廣,西條芳文
  • Organizer: 生体医工学シンポジウム2012
  • Place of Presentation: 大阪
  • Year and Date: 20120907-20120908
• [Presentation] 光音響顕微鏡によるマウス膝軟骨の観察 (2012)
  • Author(s): 和泉拓哉,三井田佑輔,長岡亮,久保聖乃,小島貴則,佐藤みか,萩原嘉廣,西條芳文
  • Organizer: 日本超音波医学会第85回学術集会
  • Place of Presentation: 東京
  • Year and Date: 20120525-20120527
• [Presentation] 半導体レーザーを用いた光音響顕微鏡によるラット膝関節の評価 (2012)
  • Author(s): 和泉拓哉,佐藤みか,長岡亮,萩原嘉廣,西條芳文
  • Organizer: 東北大学電気通信研究所超音波エレクトロニクス研究会(共催:日本超音波医学会基礎技術研究会、第四回アコースティックイメージング研究会)
  • Place of Presentation: 仙台
  • Year and Date: 2012-12-13