2012 Fiscal Year Final Research Report
Reconstruction of spinal cord function using collagen filaments
| Project/Area Number |
23791647
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Yamaguchi University |
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Principal Investigator |
SUZUKI Hidenori 山口大学, 大学院・医学系研究科, 助教 (30393432)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 脊髄損傷 / scaffold / allodynia |
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| Research Abstract |
We obtained a lot of basic knowledge of the methods of anesthesia and management after surgery, and how to make the monkey’s SCI model. And on allodynia we made good scale using rat and mouse SCI models. In addition we succeeded to show the degree of allodynia using our new scale objectively. On CF transplantation to monkey SCI model, the results of tissue analysis were excellent and we confirmed that regenerated axons went through into the Collagen Filaments same as rat models in acute phase. But this is only analysis in a short term, so we have little data about motor functional recovery. This is the next theme and task for us.
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