2012 Fiscal Year Final Research Report
Analysis of effects of anesthetic agent on rat somatosensory cortexusing in vivo patch clamp recording
| Project/Area Number |
23791710
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kyushu University |
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Principal Investigator |
SHIOKAWA Hiroaki 九州大学, 大学院・医学研究院・麻酔蘇生学, 助教 (30572490)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 疼痛管理学 |
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| Research Abstract |
In this project, in vivo whole-cell patch-clamp recordings were performed from primary somatosensoryneurons which responded to the mechanical stimuli to the receptive field of the hind paw area.Propofol, pentobarbital, remifentanil or ketaminewas administered intravenously to the rat after starting recordings. We evaluated the effect of these anesthetic agents by analyzing the responses evoked by pinch stimuli
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