2012 Fiscal Year Final Research Report
Effect of opioids on tumor growth and stem cell differentiation
| Project/Area Number |
23791731
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Keio University |
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Principal Investigator |
KUZUMAKI Naoko 慶應義塾大学, 医学部, 特任助教 (10507669)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 麻酔学 / オピオイド / がん細胞 / GPCR |
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| Research Abstract |
To determine the expression profile of GPCRs in gefitinib-sensitive (HCC827) and gefitinib-resistant NSCLC cells (H1975, HCC827GR), a GPCR-specific microarray analysis was performed. A heat-map of the microarray revealed considerable differences in the ex
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[Journal Article] Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer.2012
Author(s)
Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Suzuki T, Okada Y, Okano HJ, Yamashita JK, Okano H, Narita M.
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Journal Title
PLoS One
Volume: 7(10)
Pages: e44368
DOI
Peer Reviewed
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[Journal Article] Effect of kappa-opioid receptor agonist on the growth of non-small cell lung cancer (NSCLC) cells.2012
Author(s)
Kuzumaki N, Suzuki A, Narita M, Hosoya T, Nagasawa A, Imai S, Yamamizu K, Morita H, Nagase H, Okada Y, Okano HJ, Yamashita JK, Okano H, Suzuki T and Narita M
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Journal Title
Br J Cancer
Volume: 106(6)
Pages: 1148-52
DOI
Peer Reviewed
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