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2012 Fiscal Year Final Research Report

Establishment of the treatment strategy for the superficial and invasive bladder cancer cell using the bafilomycin

Research Project

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Project/Area Number 23791784
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Urology
Research InstitutionKeio University

Principal Investigator

YOSHIMINE Shunsuke  慶應義塾大学, 医学部, 助教 (70445245)

Project Period (FY) 2011 – 2012
Keywords癌 / 癌治療 / 膀胱癌 / 化学療法
Research Abstract

The bafilomycin induced antitumor effect of bladder cancer cell lines through the inhibition of the Bcl-xL protein function. The Bcl-xL protein was presented at high frequency in the specimen of the upper urinary tract urothelial carcinoma and the high ex

  • Research Products

    (3 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelialcarcinoma.2013

    • Author(s)
      Shunsuke Yoshimine, Eiji Kikuchi, Takeo Kosaka, Shuji Mikami, Akira Miyajima, Yasunori Okada, Mototsugu Oya.
    • Journal Title

      British Journal of Cancer (2013)

      Pages: 1-9

    • DOI

      doi:10.1038/bjc.2013.216

    • Peer Reviewed
  • [Presentation] Prognostic significance of Bcl-xL protein expression on survival in patents with upper tract urothelial carcinoma treated with radical nephroureterectomy.Annual Meeting of the American Urological Association.2013

    • Author(s)
      Shunsuke Yoshimine, Eiji Kikuchi, Takeo Kosaka, Shuji Mikami, Akira Miyajima, Yasunori Okada, Mototsugu Oya
    • Organizer
      Annual Meeting of the American Urological Association
    • Place of Presentation
      SAN DIEGO CA USA, San Diego Convention Center
    • Year and Date
      2013-05-05
  • [Presentation] 上部尿路上皮癌におけるBcl-xLの発現と予後との関連の検討2012

    • Author(s)
      吉峰 俊輔、菊地 栄次、小坂 威雄、宮嶋哲、大家 基嗣
    • Organizer
      第100回日本泌尿器科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-04-22

URL: 

Published: 2014-09-25  

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