2012 Fiscal Year Final Research Report
Liposomal PTEN Gene Therapy in an Orthotopic Bladder Cancer Modeland Prevention of Tumor Invasion and Metastasis
| Project/Area Number |
23791786
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Urology
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| Research Institution | Keio University |
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Principal Investigator |
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| Research Collaborator |
KIKUCHI Eiji 慶應義塾大学, 医学部, 講師 (10286552)
MIYAJIMA Akira 慶應義塾大学, 医学部, 講師 (90245572)
OYA Mototsugu 慶應義塾大学, 医学部, 教授 (00213885)
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| Project Period (FY) |
2011 – 2012
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| Keywords | PTEN / 遺伝子治療 / 免疫治療 / 筋層非浸潤性膀胱癌 |
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| Research Abstract |
Efficient gene transfection of LacZ reporter plasmid to MBT2variant cells using a reagent GenePORTER3000 was confirmed with X-gal staining. In thesame way, we transfected PTEN plasmid to MBT2 variant cells, and observed high expressionof PTEN protein and
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