2012 Fiscal Year Final Research Report
Energy metabolism of seminiferous epithelium in spermatogenesis
| Project/Area Number |
23791793
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Urology
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| Research Institution | Fujita Health University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | アンドロロジー / 精子発生 / 脂肪酸代謝 |
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| Research Abstract |
Seminiferous epithelium is the site of spermatogenesis and is a unique environment in energy metabolism because of its separation from the blood. Such characteristics may contribute to spermatogenesis in quality or quantity. Previous study shows that Sertoli cells that surround spermatogenic cells have less gene expression level of energy production pathways except glycolysis than liver, however, they can metabolize fatty acid as another energy source. Energy or metabolite by fatty acid oxidation of Sertoli cells may be important to spermatogenesis.
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