2013 Fiscal Year Final Research Report
Functional analysis of estrogen receptor beta-targeting candidate gene Basonuclin1.
| Project/Area Number |
23791803
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 生殖 / 不妊 |
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| Research Abstract |
Basonuclin1 (Bnc1) gene is specifically expressed in germ cells and keratinocyte. We have identified the possibility of that Bnc1 gene expression is regulated by estrogen receptor beta. Our findings include: The localization of Bnc1 is slightly different from that of Bnc1 during early oocyte maturation; Bnc1 has another isoform and it localizes in cytoplasm; This isoform is specifically sumoylated with SUMO2/3.
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Research Products
(8 results)
