2013 Fiscal Year Final Research Report
The roles of PKC in regulating the function of placenta-specifictranscription factor GCMa/1
| Project/Area Number |
23791858
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kinjo Gakuin University |
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Principal Investigator |
YUKO Yasui 金城学院大学, 付置研究所, その他 (80434554)
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| Project Period (FY) |
2011 – 2012
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| Keywords | GCMa(GCM1) / 胎盤 |
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| Research Abstract |
Serines 328, 378 and 383 on GCMa are phosphorylated by the PKC- and MEK-dependent signaling pathway. The phosphorylation of GCMa contributes to enhance its degradationby increase of the ubiquitination level as well as its transcriptional activity.
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