2012 Fiscal Year Final Research Report
Pathologic Elucidation of Olfactory Disorder Using Mass Spectrometry
| Project/Area Number |
23791897
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kobe University |
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Principal Investigator |
DOI Kiyoshi 神戸大学, 大学院・医学研究科, 助教 (00379380)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 嗅覚障害 / マイクロアレイ・BDNF |
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| Research Abstract |
The olfactory receptor neurons have an unusual characteristic of continuous neurogenesis throughout its lifetime. We observed a dynamic state of gene in the regeneration process of olfactory receptor neurons. From this observation, it was suggested that BDNF, that is known as a neurotrophic factor participates to the olfactory regeneration process at early phase in the olfactory epithelium and at late phase in the olfactory bulb.
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