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2012 Fiscal Year Final Research Report

Analysis of pathology and development of treatment for dry age-related macular degeneration using adaptive optics scanning laser ophthalmoscopy

Research Project

  • PDF
Project/Area Number 23791979
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionKyoto University

Principal Investigator

OOTO Sotaro  京都大学, 医学研究科, 助教 (10511850)

Project Period (FY) 2011 – 2012
Keywords加齢黄斑変性 / 眼底イメージング / 視細胞 / 補償光学
Research Abstract

We investigated the pathology and the mechanism of progressionof dry age-related macular degeneration at the cellular level using adaptive optics scanning laser ophthalmoscopy . Cone density was decreased and cone arrangement was irregular, and cone density correlated with visual function in dry age-related macular degeneration. This study proposed the evaluation of the treatment for this disease.

  • Research Products

    (9 results)

All 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (5 results)

  • [Journal Article] Photoreceptor damage and foveal sensitivity in surgically closed macular holes: an adaptive optics scanning laser ophthalmoscopy study2012

    • Author(s)
      Ooto S et al
    • Journal Title

      Am J Ophthalmol

      Volume: 154 Pages: 174-186

    • DOI

      DOI:10.1016/j.ajo.2012.01.031

    • Peer Reviewed
  • [Journal Article] High-resolution imaging of the retinalnerve fiber layer in normal eyes using adaptive optics scanning laser ophthalmoscopy2012

    • Author(s)
      Takayama K, Ooto S, et al
    • Journal Title

      PLOS ONE

      Volume: 7 Pages: e33158

    • DOI

      DOI:10.1371/journal.pone.0033158

    • Peer Reviewed
  • [Journal Article] Assessment of macular choroidal thickness by optical coherence tomography and angiographic changes in central serous chorioretinopathy2012

    • Author(s)
      Jirarattanasopa P, Ooto S, et al
    • Journal Title

      Ophthalmology

      Volume: 119 Pages: 1666-1678

    • DOI

      DOI:10.1016/j.ophtha.2012.02.021

    • Peer Reviewed
  • [Journal Article] Choroidal thickness, vascular hyperpermeability, and complement factor h in age-related maculardegeneration and polypoidal choroidal vasculopathy2012

    • Author(s)
      Jirarattanasopa P, Ooto S, et al
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 53 Pages: 3663-3672

    • DOI

      DOI:10.1167/iovs.12-9619

    • Peer Reviewed
  • [Presentation] High-resolution Photoreceptor Imaging of Macular Microholes Using Adaptive Optics Scanning Laser Ophthalmoscopy2012

    • Author(s)
      Ooto S, et al
    • Organizer
      American Academy of Ophthalmology
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2012-11-11
  • [Presentation] シンポジウム 眼光学から考える眼底イメージング「 Adaptive Optics」2012

    • Author(s)
      大音壮太郎
    • Organizer
      第66回日本臨床眼科学会総会
    • Place of Presentation
      京都
    • Year and Date
      2012-10-26
  • [Presentation] SIG 黄斑研究会シンポジウム 網膜形態評価法はどこまで進歩したか「補償光学 視細胞」2012

    • Author(s)
      大音壮太郎
    • Organizer
      第66回日本臨床眼科学会総会
    • Place of Presentation
      京都
    • Year and Date
      2012-10-25
  • [Presentation] 視機能研究会シンポジウム画像は機能を推し量れるか「黄斑上膜における視細胞配列異常」2012

    • Author(s)
      大音壮太郎
    • Organizer
      第60回日本視覚電気生理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-10-06
  • [Presentation] サブスペシャリティサンデー 後眼部疾患 網膜疾患:手術システム・診断機器の進歩「形態学的診断機器の進歩」2012

    • Author(s)
      大音壮太郎
    • Organizer
      第66回日本眼科学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-08

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Published: 2014-09-25  

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