2012 Fiscal Year Final Research Report
Regeneration of retinal function using human amnion cell-derived neural progenitors.
| Project/Area Number |
23792013
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Nippon Medical School |
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Principal Investigator |
KITAHARA Yuki 日本医科大学, 医学部, 助教 (30360176)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 再生医学 / 網膜再生 / 神経幹細胞 / 羊膜由来幹細胞 |
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| Research Abstract |
Human amniotic membrane is already broadly transplanted to the ocular surface , the supply is abundant and is easy to obtain. Human amnion cell-derived neural progenitors can be isolated and cultured from human amnion obtained during cesarean section under the informed consent. Human amnion cell-derived neural progenitors obtain long-term survival in the subretinal space and possess the potential of differentiating to retinal cells. Regeneration of retinal function was suggestive using electroretinogram.
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