2013 Fiscal Year Final Research Report
The influence of human adipose-derived stem cells against Squamous Cell Carcinoma
| Project/Area Number |
23792064
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Juntendo University (2012-2013)
Nippon Medical School (2011) |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 脂肪組織幹細胞 / 扁平上皮癌 / 動物実験 |
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| Research Abstract |
This research was to investigate the influence of adipose-derived stem cells (ASCs) against the tumor development of squamous cell carcinoma (SCC) cells. SCC cells with or without ASCs have been transplanted into the abdominal subcutaneous tissue of experimental animals. The experimental groups were prepared as follows; 1: SCC cells transplantation; 2: Co-transplantation of SCC cells with ASCs; 3: SCC cells and ASCs transplantation into different site; and 4: SCC cells transplantation and ASCs administration. After 12 weeks of cells injection, no significant differences for the tumor development were seen between the SCC cells transplantation and other co-transplantation groups.
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