2012 Fiscal Year Final Research Report
Lineage analysis of cells involved in bone formation using the ectopic bone model in which prepared bone marrow stromal cells were transplanted in rats
| Project/Area Number |
23792066
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Kurume University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 細胞培養 / 移植学 / 間葉系幹細胞 / 再生医学 / 形態 |
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| Research Abstract |
In our research, we employed bone marrow stromal cells that expressed Enhanced Green Flourescent Protein (EGFP) as a reporter molecule to observethe formation and organization of subcutaneous ectopic bone tissues in rats backs andto verify the origin of those cells. The results showed an even proportion of donor cellsand recipient cells in the organization of ectopic bone tissues. It was also confirmedthat some of the recipient cells were originated from fibroblasts.
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