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2013 Fiscal Year Final Research Report

The development of the plasma endotoxin assay by ESP using the protein addition preparation

Research Project

  • PDF
Project/Area Number 23792082
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Emergency medicine
Research InstitutionIwate Medical University

Principal Investigator

TAKAHASHI Gaku  岩手医科大学, 救急医学講座, 助教 (60453304)

Co-Investigator(Renkei-kenkyūsha) KOJIKA Masahiro  岩手医科大学, 救急医学講座, 助教 (40347878)
SUZUKI Yasushi  岩手医科大学, 救急医学講座, 助教 (90306019)
ONODERA Chiaki  岩手医科大学, 救急医学講座, 助教 (30633078)
Project Period (FY) 2011 – 2013
Keywordsエンドトキシン / ESP / アルブミン / 比濁時間分析法
Research Abstract

Though The conventional automated turbidimetric-kinetic assay required 119 minutes to measure endotoxin of 1.0pg/ml, but measurement time was shortened more than 30 minutes by ESP using the protein addition preparation , the sensitivity of the measurement increased as compared with a traditional approach, too.

  • Research Products

    (4 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Evalution of an endotoxin-specific limulus amebocyte lysate assay using leukocyte-rich plasma for the diagnosis of gram-negative bacterial infection2013

    • Author(s)
      Shigenori Kan 、Gaku Takahashi,et al
    • Journal Title

      Infect Chemother

      Volume: 19 Pages: 299-304

    • Peer Reviewed
  • [Presentation] ヒト血清アルブミン添加法を用いたESP法でのエンドトキシン測定法の検討2012

    • Author(s)
      高橋 学
    • Organizer
      エンドトキシン血漿救命治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-27
  • [Presentation] 高輝度ルシフェラーゼを用いた新しいエンドトキシン測定法の開発2012

    • Author(s)
      小野寺ちあき
    • Organizer
      エンドトキシン血漿救命治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-27
  • [Patent(Industrial Property Rights)] 生物由来の生理活性物質の測定方法および測定装置2012

    • Inventor(s)
      稲田捷也
    • Industrial Property Rights Holder
      稲田捷也
    • Industrial Property Number
      2012-15481
    • Acquisition Date
      2012-08-16

URL: 

Published: 2014-09-25  

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