Study on the cerebral and systemic changes caused by chewing of the foods with different taste and odor

2012 Fiscal Year Final Research Report

• Project/Area Number: 23792263
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthetic dentistry
• Research Institution: Hyogo Medical University
• Principal Investigator: HASEGAWA Yoko 兵庫医科大学, 医学部, 助教 (60432457)
• Project Period (FY): 2011 – 2012
• Keywords: 咀嚼 / 味と香り / 脳血流 / ストレス / 情動

Research Abstract

In this study, we examined the changes in cerebral blood flow, systemic circulation, and autonomic nerve activity (heart rate and blood pressure variability analysis) during chewing of gum with various tastes and odors in order to investigate the effect of changes in taste and odor on these values. The result was that chewing of gum with taste and odor increased the cerebral blood flow most, suggesting that intake of foods with taste is important for activation of circulation system such as cerebral circulation. Furthermore, we measured the amount of secreted cortisol in saliva during chewing of gum in order to investigate the stress response to the chewing of gum with different tastes and odors. The results was that the gum with sweetness and lemon odor tasted best, and when chewing this gum, the amount of saliva secreted during chewing and the concentration of cortisol in saliva were higher than when chewing the other five gums. These results indicated that chewing of gum withtaste and odor, which was delicious for the subjects, causes more secretion of cortisol, an anti-stress hormone.

Research Products

• [Journal Article] Flavor-enhanced modulation of cerebral blood flow during gum chewing. (2013)
  • Author(s): Hasegawa Y, Tachibana Y, Sakagami J, Zhang M, Urade M, Ono T.
  • Journal Title: PLOS ONE.
  • URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066313
• [Journal Article] Contrast enhanced multidetector CT for odontogenic cysts and cystic appearing tumors of the jaws: Is it useful (2013)
  • Author(s): Kakimoto N, Chindasombatjaroen J, Tomita S, Shimamoto H, UchiyamaY, Hasegawa Y, et al.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol; Volume: 115 Pages: 104-113
  • URL: http://dx.doi.org/10.1016/j.oooo.2012.09.082
• [Journal Article] Comparison of Joint Pain between Related and Unrelated to Articular Disc Displacement without Reduction in the Temporomandibular Joint. (2013)
  • Author(s): Fujiwara M, Honda K, Hasegawa Y, Hasegawa M, Urade M.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod;
  • URL: http://dx.doi.org/10.1016/j.oooo.2012.11.012
• [Journal Article] Movement of the mandibular condyle and articular disc on placement of an occlusal splint Reply. (2012)
  • Author(s): Hasegawa Y
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Volume: 113 Pages: 711-712
  • URL: http://dx.doi.org/10.1016/j.oooo.2012.02.008
• [Journal Article] Movement of the mandibular condyle and articular disc on placement of an occlusal splint (2011)
  • Author(s): Hasegawa Y, Kakimoto N, Tomita S,et al
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Volume: 112 Pages: 640-647
  • URL: http://dx.doi.org/10.1016/j.tripleo.2011.06.013
• [Presentation] 味および香りがガム咀嚼時のストレスに及ぼす影響 (2012)
  • Author(s): 長谷川陽子,橘吉寿,小野高裕.
  • Organizer: 第23回日本咀嚼学会学術大会・総会.
  • Place of Presentation: 北海道
  • Year and Date: 2012-10-13
• [Presentation] オクルーザルスプリントによる顎関節の変位が顎関節部の痛みに及ぼす影響 (2012)
  • Author(s): 長谷川陽子,柿本直也,富田世紀,本田公亮,田中裕人,小野高裕,藤原正識,前田芳信
  • Organizer: 日本補綴歯科学会平成23年度関西支部学術大会.
  • Place of Presentation: 神戸
  • Year and Date: 2012-02-13
• [Presentation] 習慣性咀嚼側が脳循環に及ぼす影響 (2011)
  • Author(s): 長谷川陽子,阪上穣,小野高裕,堀一浩,本田公亮,浦出雅裕.
  • Organizer: 日本顎口腔機能学会第47回学術大会.
  • Place of Presentation: 神戸
  • Year and Date: 2011-10-22
• [Presentation] Influence of Denture Wearing on Outcome of Treatment for Bisphosphonate-Related Osteonecrosis of the Jaws.Nationwide Survey in Japan (2011)
  • Author(s): Hasegawa Y, Kawabe M, Kimura H, Kurita K, Fukuda J, Urade M.
  • Organizer: 14th Meeting of the International College of Prosthodontists.
  • Place of Presentation: Hawaii, USA
  • Year and Date: 2011-09-09
• [Presentation] Influence of an occlusal splint on TMJ position (2011)
  • Author(s): Hasegawa Y, Kakimoto N, Tomita S,Tanaka Y, Yagi K, Nagashima T, Honda K, Ono T, Kondo J, Maeda Y, Urade M.
  • Organizer: IADR 89th General Session and Exhibition.
  • Place of Presentation: San Diego, USA
  • Year and Date: 2011-03-17