2012 Fiscal Year Final Research Report
Involvement of signal pathway and apoptosis of cardioprotection by regular ethanol consumption
| Project/Area Number |
23792395
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
KANEDA Kazuhiro 大阪歯科大学, 歯学部, 講師(非常勤) (90533886)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 虚血心筋 / 心筋保護 / エタノール / シグナル伝達 / アポトーシス |
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| Research Abstract |
Bradykinin has been implicated in ischemic preconditioning and has been shown to induce mitochondrial reactive oxygen species generation through nitric oxide (NO). I investigated the involvement of the bradykinin B2 receptor (BKB2R) and measured NO production in chronic ethanol-induced cardioprotection.
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