2014 Fiscal Year Final Research Report
Molecular pathological study of IgG4-MOLPS
| Project/Area Number |
23792404
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Aichi Gakuin University (2013-2014)
Ogaki Women's College (2011-2012) |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Keywords | IgG4関連多臓器リンパ増殖性疾患 / 免疫グロブリン遺伝子 / 自己免疫性疾患 |
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| Outline of Final Research Achievements |
IgG4-MOLPS is to suggest the involvement of a steroid-responsive autoimmune. This disease it was examined whether having the characteristics of autoimmune. Immunoglobulin gene clone, in the study of somatic mutation rate, but was not observed characteristic clone, the somatic mutation rate was the same results and autoimmune disease. However, the characteristic factor in autoimmune disease it could not be confirmed. IgG4-MOLPS from this study the possibility of recognized not autoimmune disease that strongly support an association between autoimmune disease was considered to be low.
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| Free Research Field |
口腔内科学
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